65 year old male with tremors and urinary incontinence
Patient was apparently asymptomatic 5 years ago then he developed tremors in upper limbs which was insidious in onset and gradually progressive and involved lower limbs,
3 months back his speech got slurred, drooling of saliva started,
since 2 months patient was unable to control micturition and he started to felt giddiness and falls suddenly while walking and he is complaining of constipation since 2 months
No H/O Fever, Vomitings, burning micturition,chills, SOB
Past history:
He is a K/C/O Parkinson's disease and he is using Syndopa 125 mg and trihexiphenidyl 2mg since 3 years
No history of similar complaints in the past
N/K/C/O DM,Htn,Tb,Asthma, epilepsy,CAD,
Thyroid disorders
Family history:
Not Significant
Personal History:
Diet - mixed
Appetite - normal
sleep - adequate
Bowel and Bladder movements- irregular, constipation and urinary incontinence is seen
Addictions - no
No known allergies
Drug history :
No significant drug history
General examination:
Patient is conscious ,coherent ,cooperative and was well oriented to time ,place and person at the time of examination
He is examined in a well lit room, with consent taken.
He is moderately built and moderatly nourished.
Pallor - absent
Icterus - absent
Cyanosis - absent
Clubbing - absent
lymphadenopathy - absent
Pedal edema - absent
Vitals : on the day of admission (12/11/2022)
Temperature - afebrile
Pulse rate - 82 bpm
Respiratory rate - 16 cpm
Blood pressure - 120/80 mmHg
SpO2 - 99% on Room air
GRBS - 127 mg/dl
Postural hypotension not present:
- Supine BP - 120/70mmHg & On Standing 120/80mmHg
Systemic examination:
CVS : S1 and S2 heart sounds heard
NO murmurs and thrills
RESPIRATORY SYSTEM : Bilateral air entry present position of trachea - central
Vesicular breathsounds heard
CNS : mask like expression less face is seen
Festinant gait present
Able to do finger nose test,knee heal test,no dysdiadokokinesia,
Not able to walk in a straight line
ABDOMEN :
Soft On deep palpation -non TENDER no palpable masses
Bowel sounds heard
NO organomegaly
Investigations:
On 12/11/2022:
On 13/11/2022:
HEMOGRAM:
SERUM CREATININE:SERUM ELECTROLYTES:
SERUM CALCIUM:
COMPLETE URINE EXAMINATION:
BLOOD SUGAR-RANDOM:
BLOOD UREA:
LIVER FUNCTION TEST:
Anti HCV Antibodies-RAPID:HBsAg-RAPID:
HIV1/2 RAPID :
X-ray :
Ultrasound Report:
ECG Report:
On 14/11/2022:
Diagnosis:
Parkinson's disease
Treatment:
1)Tab.Syndopa 125 mg PO/TD
2)Tab.Trihexyphenidyl 2 mg PO/BD
3)Inj. Optineuron 1amp in 500ml NS IV/OD
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